MARC details
| 000 -LEADER |
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| fixed length control field |
03480nab a2200361 i 4500 |
| 001 - CONTROL NUMBER |
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| control field |
a426952 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
SIRSI |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
200706s2007 xxu |s 000#0 eng d |
| 009 - PHYSICAL DESCRIPTION FIXED-FIELD FOR ARCHIVAL COLLECTION (VM) [OBSOLETE] |
|---|
| fixed length control field |
426952 |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EBSCO |
| Language of cataloging |
fre |
| Transcribing agency |
EBSCO |
| Modifying agency |
FRAS |
| Description conventions |
AFNOR |
| 043 ## - GEOGRAPHIC AREA CODE |
|---|
| Geographic area code |
f-ti--- |
| 072 ## - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
OM |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
362.109611 |
| Edition number |
21E |
| 084 ## - OTHER CLASSIFICATION NUMBER |
|---|
| Classification number |
362 |
| 035 ## - SYSTEM CONTROL NUMBER |
|---|
| System control number |
949172332 |
| 095 ## - 095 |
|---|
| a |
xxu |
| 100 10 - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Hadrich, Ines |
| Relator term |
Auteur |
| Relationship |
070 |
| 9 (RLIN) |
291146 |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Ethnic and socio-cultural specificities in Tunisia have no impact on the prevalence of anti-Saccharomyces cerevisiae antibodies in Crohn's disease patients, their relatives or associated clinical factors |
| Medium |
[Ressource électronique] |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Background. In Western Europe and the USA, the presence of anti-Saccharomyces cerevisiae antibodies (ASCAs) in Crohn's disease (CD) patients and their healthy relatives suggests that ASCAs may be influenced by genetic and/or environmental factors. Objectives. To assess the prevalence of ASCAs in Tunisian patients with CD or ulcerative colitis (UC), and unaffected family members, in relation to clinical phenotype. Patients and methods. Seventy-seven patients (39 CD, 38 UC), 66 healthy relatives of CD patients, 16 relatives of UC patients and 70 healthy controls were studied. ASCAs were quantified with a new isotype-specific ELISA test involving an antigenic extract from S. cerevisiae strain W303 and by the original test which detects total immunoglobulins against S. cerevisiae Su1 mannan. Results. The specificity of the two tests was identical (91%). The isotype-specific ASCA W303 test was more sensitive than the ASCA Su1 test for immunoglobulin detection, but some CD patients were positive only with this latter test. A high percentage of patients with CD (72%) and their unaffected family members (35%) were ASCA-positive in contrast to UC patients (16%) and their relatives (0%) and controls (8.6%). ASCAs were shown to be independent of rural or urban living, disease activity, but were associated with ileal location. The antigen of S. cerevisiae strain W303 discriminated patients depending on age at onset or location of the disease. Conclusion. This study confirms the antigenic heterogeneity of S. cerevisiae strains in their ability to detect ASCA. It suggests that ASCAs are markers of immunoregulatory disturbance in CD, independently of ethnic/cultural differences between Europe, the USA and North Africa. [ABSTRACT FROM AUTHOR] |
| Expansion of summary note |
Copyright of Scandinavian Journal of Gastroenterology is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
MALADIE |
| 9 (RLIN) |
1249 |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
GROUPE ETHNO CULTUREL |
| 9 (RLIN) |
2367 |
| 651 #4 - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
|---|
| Geographic name |
TUNISIE |
| 9 (RLIN) |
1128 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Vandewalle, Peggy |
| Relator term |
Auteur |
| Relationship |
070 |
| 9 (RLIN) |
291147 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Sendid, Boualem |
| Relator term |
Auteur |
| Relationship |
070 |
| 9 (RLIN) |
291148 |
| 773 ## - HOST ITEM ENTRY |
|---|
| Title |
Scandinavian Journal of Gastroenterology |
| Related parts |
Jun. 2007, Vol. 42 Issue 6, p717-725 |
| International Standard Serial Number |
ISSN 00365521 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
<a href="http://www.fondation.org.ma/dsp/index/a426952-20">http://www.fondation.org.ma/dsp/index/a426952-20</a> |
| 930 ## - EQUIVALENCE OR CROSS-REFERENCE-UNIFORM TITLE HEADING [LOCAL, CANADA] |
|---|
| Uniform title |
426952 |
| 931 ## - |
|---|
| -- |
a426952 |
| 990 ## - EQUIVALENCES OR CROSS-REFERENCES [LOCAL, CANADA] |
|---|
| Link information for 9XX fields |
El Basri |
